Institut Charles Sadron Event

Lipid membranes play a central role in many biological processes, including endocytosis and the entry of certain pathogens. This thesis explores, through a primarily experimental approach, the interactions between synthetic microparticles, either passive or self-propelled, and model membranes in the form of lipid vesicles. By varying the size, shape, and surface chemistry of the particles, the membrane composition, and the properties of the surrounding medium, we highlight the fundamental role of non-specific physical forces in governing particle-membrane interactions. This work contributes to a better understanding of the underlying biophysical mechanisms and opens new perspectives for the design of biomimetic systems in synthetic biology and nanomedicine.